Epidemiological aspects of the association of the hypertriglyceridemic waist phenotype with metabolic syndrome and cardiovascular risk factors in Morocco. Case the Amazigh population from a geographic region called Souss
Więcej
Ukryj
1
Cellular Biology and Molecular Genetics Laboratory, Sciences Faculty, Ibn Zohr University, Morocco
2
Medical Biology Unit, Provincial Hospital Hassan 1er, Tiznit, Morocco
3
Sciences of Health and Environment Laboratory, Team of Biotechnology, Environment and Health,
Higher Institute of Nursing Professions and Health Techniques (ISPITS), Morocco
Data nadesłania: 18-05-2024
Data ostatniej rewizji: 05-07-2024
Data akceptacji: 06-07-2024
Data publikacji online: 25-07-2024
Data publikacji: 14-08-2024
Autor do korespondencji
Hamid Najeh
1 Cellular Biology and Molecular Genetics Laboratory, Sciences Faculty, Ibn Zohr University,, 80000, Agadir, Morocco
Rocz Panstw Zakl Hig 2024;75(2):185-193
SŁOWA KLUCZOWE
DZIEDZINY
STRESZCZENIE
Background: The global prevalence of metabolic syndrome (MetS) increases susceptibility to non-communicable
diseases such as obesity, type 2 diabetes, and cardiovascular disease, posing significant health risks. Effective prevention
and management require objective tools. The hypertriglyceridemic waist (TG+WC+) phenotype is proposed as a less
expensive approach to identify individuals with metabolic syndrome and other cardiovascular risk factors. Objective: The current aim of this investigation is to study the epidemiological characteristics of the hypertriglyceridemic
waist phenotype and their correlations with cardiovascular risk factors and MetS in the Moroccan Amazigh ethnic group
from the Souss region of Morocco. Material and Methods: A total of 827 Amazigh adults from the Sousse region of Morocco were divided into four distinct phenotype groups: TG-WC-, TG+WC-, TG-WC+, and TG+WC+ (normal TG- or high TG+ triglycerides/normal WC- or
high WC+ waist circumference). The association of the different phenotypes with MetS and other cardiovascular risk
factors was established by logistic regression analysis. Results: The prevalence of the TG+WC+ phenotype was 27.7% and varied according to age group and sex. Among
subjects with the TG+WC+ phenotype, most were 41-60 years old (53.3%) and in women (74.2%). Participants with the
TG+WC+ phenotype had the highest prevalence of dyslipidemia (87.3%), hypoHDLaemia (69.9%), and general obesity
(37.12%). The three phenotypes TG-WC-, TG+WC- and TG-WC+ were less associated with MetS and other cardiovascular
risk factors. Moreover, people with the TG+WC+ phenotype had a very high odds ratio for MetS. Conclusion: These findings suggest that the TG+WC+ phenotype exhibits a robust correlation with MetS and additional
variables connected to cardiovascular risk. The TG+WC+ phenotype serves as a valuable clinical instrument for detecting
individuals vulnerable to MetS and cardiovascular diseases.